Tumor necrosis factor alpha induces p53 up-regulated modulator of apoptosis expression in colorectal 1. Dis Colon Rectum. 2010 Mar;53(3):257-63. doi: 10.1007/DCR.0b013e3181c522c7. Tumor necrosis factor alpha induces p53 up-regulated modulator of apoptosis expression in colorectal cancer cell lines. Pastor DM, Irby RB, Poritz LS. PURPOSE: Inflammatory ...
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization : Article : Nature Figure 1: Purification of HAUSP, and interactions between p53 and HAUSP. a, Identification of HAUSP as a novel p53-binding protein. Silver staining analysis of an SDS–PAGE gel containing the eluates from the indicated columns. Peptide sequences derived fr
Inhibition of SIRT1 Catalytic Activity Increases p53 Acetylation but Does Not Alter Cell Survival fo Deacetylation assays and inhibitory compounds. Deacetylation was measured using the Fluor de Lys kit (AK-555; Biomol) using a fluorogenic peptide encompassing residues 379 to 382 of p53, acetylated on lysine 382 (KI-177; Biomol). The acetylated lysine ...
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